Saphris (asenapine) is an atypical antipsychotic medication that is approved for the treatment of bipolar disorder. It is typically used to manage acute manic or mixed episodes associated with bipolar I disorder in adults.
Saphris is available as a sublingual tablet that is placed under the tongue and allowed to dissolve. The medication is rapidly absorbed through the sublingual mucosa, which allows for a quicker onset of action compared to other oral medications.
Saphris Dosages
The usual starting dose of Saphris (asenapine) for the treatment of acute manic or mixed episodes associated with bipolar I disorder in adults is 5 mg twice daily. The maximum recommended daily dose is 20 mg.
However, the actual dosage of Saphris may vary depending on the individual’s response to the medication and other factors such as age, weight, and medical history. The healthcare provider may adjust the dosage of Saphris based on the individual’s symptoms, tolerance to the medication, and any potential side effects.
It is important to take Saphris as prescribed by a healthcare provider and to follow their instructions closely. The medication is available as a sublingual tablet that is placed under the tongue and allowed to dissolve. Individuals should avoid eating or drinking for 10 minutes after taking the medication to allow for optimal absorption.
Possible Side Effects of Saphris
Some common side effects of Saphris include:
- Drowsiness
- Dizziness
- Insomnia
- Headache
- Nausea
- Vomiting
- Dry mouth
- Tiredness
- Restlessness
- Tremors
- Constipation
- Weight gain
Less common but more serious side effects of Saphris can include:
- Allergic reactions, such as hives, rash, itching, or difficulty breathing
- Movement disorders, such as tardive dyskinesia (uncontrollable movements of the face, tongue, or other body parts)
- Low white blood cell count, which can increase the risk of infection
- Increased blood sugar levels, which can lead to diabetes or worsen pre-existing diabetes
- Neuroleptic malignant syndrome, a rare but serious condition that can cause fever, muscle rigidity, and other symptoms
It is important to contact a healthcare provider immediately if any of these serious side effects occur. The provider can determine the appropriate course of action, which may include adjusting the dosage or switching to a different medication.